Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17986551 | 0.91 | LIMK2 (0.33) | CETPLIMK2 | |
| SCHEMBL16630680 | 0.90 | CETP (0.34) | CETPLIMK2 | |
| SCHEMBL16629857 | 0.87 | CETP (0.36) | CETPLIMK2 | |
| SCHEMBL16619381 | 0.87 | CETP (0.36) | CETPLIMK2 | |
| SCHEMBL18017460 | 0.87 | CETP (0.34) | CETPLIMK2 | |
| SCHEMBL17986536 | 0.87 | CETP (0.35) | CETPLIMK2 | |
| SCHEMBL17986544 | 0.86 | GPR119 (0.39) | CETPLIMK2 | |
| SCHEMBL16620144 | 0.86 | GPR119 (0.39) | CETPLIMK2 | |
| SCHEMBL17986542 | 0.86 | GPR119 (0.39) | CETPLIMK2 | |
| SCHEMBL16630653 | 0.85 | CNR1 (0.33) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015050798-A1 | NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2015-04-09 | — | — | WO | disclosed |