Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | FASN | P49327 | 3/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.32 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.32 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16619698 | 0.81 | ALB (0.54) | ALBPOLBMAPTMGLL | |
| SCHEMBL16619924 | 0.78 | ALB (0.61) | ALBALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL16619938 | 0.68 | ALB (0.58) | ALBPOLBMAPTALDH1A1HPGD | |
| SCHEMBL16619766 | 0.65 | ALB (0.67) | ALBPOLBMAPTALDH1A1HPGD | |
| SCHEMBL16630761 | 0.60 | ALB (0.86) | ALBLMNAMGLL | |
| SCHEMBL16619189 | 0.58 | SMN1; SMN2 (0.57) | ALBMAPTLMNASMN1; SMN2 | |
| SCHEMBL10064731 | 0.58 | SMN1; SMN2 (0.84) | POLBALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL28984149 | 0.58 | SMN1; SMN2 (0.84) | POLBALDH1A1HPGDLMNASMN1; SMN2 | |
| SCHEMBL4735653 | 0.58 | HSD11B1 (0.60) | POLBMAPTTP53ALDH1A1HPGD | |
| SCHEMBL4196551 | 0.57 | FASN (0.65) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015049651-A1 | COMPOUNDS FOR AFFINITY CHROMATOGRAPHY AND FOR EXTENDING THE HALF-LIFE OF A THERAPEUTIC AGENT | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2015-04-09 | — | — | WO | disclosed |