Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17954208 | 0.86 | BCL2 (0.47) | PTGER4PTGER3BCL2FFAR1AKR1B1 | |
| SCHEMBL17954222 | 0.75 | FFAR1 (0.52) | BCL2FFAR1AKR1B1FFAR4PTGS2 | |
| SCHEMBL16631080 | 0.74 | MAOB (0.47) | FFAR1AKR1B1FFAR4F2RXRA | |
| SCHEMBL9464001 | 0.74 | MAOB (0.49) | FFAR1FFAR4PTGS2F2 | |
| SCHEMBL18102828 | 0.74 | MRGPRX4 (0.62) | PTGER4BCL2FFAR1AKR1B1FFAR4 | |
| SCHEMBL4090500 | 0.73 | ABL1 (0.59) | BCL2FFAR1PTGS2PPARD | |
| SCHEMBL12585463 | 0.72 | GSTP1 (0.54) | PTGER4PTGER3FFAR1AKR1B1FFAR4 | |
| SCHEMBL695715 | 0.72 | SMN1; SMN2 (0.50) | FFAR1FFAR4PTGS2F2NR4A2 | |
| SCHEMBL26774780 | 0.72 | CYSLTR1 (0.59) | — | |
| SCHEMBL3037130 | 0.72 | BCL2 (0.67) | BCL2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051045-A2 | 3'END CAPS FOR RNAi AGENTS FOR USE IN RNA INTERFERENCE | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |