Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SOD1 | P00441 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15309991 | 0.95 | MAOB (0.50) | MAOBF2RXRARXRBTP53 | |
| SCHEMBL12585463 | 0.86 | GSTP1 (0.54) | MAOBFFAR1F2AKR1B1FFAR4 | |
| SCHEMBL17954211 | 0.85 | FFAR1 (0.48) | MAOBFFAR1F2RXRARXRB | |
| SCHEMBL27889682 | 0.83 | MAOB (0.48) | MAOBFFAR1F2RXRARXRB | |
| SCHEMBL12806827 | 0.80 | RXRA (0.60) | MAOBFFAR1RXRARXRBTP53 | |
| SCHEMBL12600515 | 0.80 | NOS1 (0.52) | MAOBF2RXRARXRBTP53 | |
| SCHEMBL1775149 | 0.79 | MAOB (0.58) | MAOBFFAR1F2SMN1; SMN2PTPRC | |
| SCHEMBL8276174 | 0.78 | RXRA (0.53) | MAOBF2RXRARXRBTP53 | |
| SCHEMBL3920123 | 0.78 | MRGPRX4 (0.59) | MAOBFFAR1F2FFAR4TP53 | |
| SCHEMBL13258018 | 0.77 | GSTP1 (0.58) | MAOBFFAR1FFAR4SMN1; SMN2GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051045-A2 | 3'END CAPS FOR RNAi AGENTS FOR USE IN RNA INTERFERENCE | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |