Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 1/20 | 0.33 |
| ▸ | TK1 | P04183 | 1/20 | 0.33 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.32 |
| ▸ | FUT6 | P51993 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631346 | 0.86 | — | — | |
| SCHEMBL16631476 | 0.81 | TK2 (0.42) | TK2TK1KCNMA1ADORA3ADORA1 | |
| SCHEMBL16631373 | 0.79 | — | — | |
| SCHEMBL18080086 | 0.79 | P2RY2 (0.44) | FUT6 | |
| SCHEMBL16631348 | 0.79 | GGPS1 (0.31) | CYP19A1 | |
| SCHEMBL16631280 | 0.74 | ADORA3 (0.41) | TK2TK1KCNMA1CYP19A1ADORA3 | |
| SCHEMBL16631859 | 0.74 | GLA (0.33) | TK2TK1 | |
| SCHEMBL18080069 | 0.73 | P2RY2 (0.44) | FUT6 | |
| SCHEMBL16631473 | 0.72 | ADORA3 (0.35) | ADORA3ADORA1 | |
| SCHEMBL18080078 | 0.71 | P2RY2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |