Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNK | O75909 | 2/20 | 0.32 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631757 | 0.80 | ADORA2A (0.46) | CCNKCDK12 | |
| SCHEMBL18081818 | 0.77 | AXL (0.34) | AXLNUDT1 | |
| SCHEMBL18080595 | 0.72 | ADORA2A (0.34) | AXLNUDT1 | |
| SCHEMBL16631753 | 0.62 | ADORA2A (0.49) | CCNKCDK12 | |
| SCHEMBL13183286 | 0.62 | BRD4 (0.42) | AXLNUDT1 | |
| SCHEMBL21418802 | 0.61 | CDK1 (0.34) | — | |
| SCHEMBL4167148 | 0.61 | AXL (0.41) | AXLNUDT1 | |
| SCHEMBL18081928 | 0.60 | ADORA2A (0.50) | AXL | |
| SCHEMBL9409341 | 0.59 | KDM4E (0.36) | — | |
| SCHEMBL24794159 | 0.59 | CCNK (0.37) | CCNKCDK12AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |