Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CCNK | O75909 | 2/20 | 0.33 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631757 | 0.85 | ADORA2A (0.46) | ADORA2AADORA1KDM4ECCR8DYRK1A | |
| SCHEMBL18081979 | 0.79 | ADORA2A (0.53) | ADORA2AADORA1KDM4ECCR8DYRK1A | |
| SCHEMBL18080573 | 0.75 | ADORA2A (0.50) | ADORA2AADORA1KDM4ECCR8DYRK1A | |
| SCHEMBL16631756 | 0.73 | ADORA1 (0.34) | ADORA2AADORA1LMNA | |
| SCHEMBL18081928 | 0.70 | ADORA2A (0.50) | ADORA2AADORA1KDM4ECCR8DYRK1A | |
| SCHEMBL811103 | 0.68 | ADORA2A (0.47) | ADORA2AADORA1KDM4ECCR8KMT2A | |
| SCHEMBL16631558 | 0.68 | SMN1; SMN2 (0.32) | KMT2ASMN1; SMN2ALDH1A1MEN1ABCC4 | |
| SCHEMBL16631774 | 0.68 | MEN1 (0.33) | KDM4EKMT2ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL16631758 | 0.67 | LMNA (0.30) | LMNA | |
| SCHEMBL18080575 | 0.67 | ADORA2A (0.48) | ADORA2AADORA1KDM4ECCR8DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |