Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UPP1 | Q16831 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | GNRHR | P30968 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | BRD2 | P25440 | 2/20 | 0.32 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.32 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18081925 | 0.84 | MAPK1 (0.31) | UPP1MAPK1 | |
| SCHEMBL18080360 | 0.81 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL23957853 | 0.76 | MAPK1 (0.43) | UPP1MAPK1SMN1; SMN2PDE4AADORA2A | |
| SCHEMBL17379726 | 0.72 | UPP1 (0.41) | UPP1MAPK1SMN1; SMN2 | |
| SCHEMBL16631396 | 0.71 | MAPK1 (0.55) | MAPK1 | |
| SCHEMBL18080406 | 0.68 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL2183944 | 0.66 | MAPK1 (0.61) | MAPK1SMN1; SMN2 | |
| SCHEMBL16631688 | 0.65 | — | — | |
| SCHEMBL18081774 | 0.65 | AMY1A (0.33) | PDE4AADORA2APDE4BPDE4CPDE4D | |
| Ammonia Solution, Strong SCHEMBL4194711 | 0.64 | MAPK1 (0.59) | MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |