Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PAM | P19021 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9324208 | 0.94 | DGKA (0.55) | DGKATSHRDNM1NAAACYP3A4 | |
| SCHEMBL446057 | 0.94 | DGKA (0.57) | DGKATSHRDNM1NAAACYP3A4 | |
| SCHEMBL17375071 | 0.94 | DGKA (0.63) | DGKATSHRDNM1NAAACYP3A4 | |
| SCHEMBL16837163 | 0.94 | DGKA (0.63) | DGKATSHRDNM1NAAACYP3A4 | |
| SCHEMBL1302517 | 0.94 | DGKA (0.63) | DGKATSHRDNM1NAAACYP3A4 | |
| SCHEMBL9839988 | 0.92 | DGKA (0.73) | DGKATSHRDNM1NAAACYP3A4 | |
| SCHEMBL8172950 | 0.92 | DGKA (0.67) | DGKATSHRDNM1NAAACYP3A4 | |
| SCHEMBL181591 | 0.92 | DGKA (0.61) | DGKATSHRDNM1NAAACYP3A4 | |
| SCHEMBL439161 | 0.92 | DGKA (0.73) | DGKATSHRDNM1NAAACYP3A4 | |
| SCHEMBL2137479 | 0.92 | DGKA (0.67) | DGKATSHRDNM1NAAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |