Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 6/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | MTOR | P42345 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2579427 | 1.00 | DNMT1 (0.35) | DNMT1ADRB1TLR7ALBDNMT3B | |
| SCHEMBL2580902 | 0.88 | DNMT1 (0.37) | DNMT1ADRB1TLR7ALBDNMT3B | |
| SCHEMBL2580901 | 0.88 | DNMT1 (0.37) | DNMT1ADRB1TLR7ALBDNMT3B | |
| SCHEMBL2584850 | 0.88 | LMNA (0.33) | SLC29A1LMNAALDH1A1 | |
| SCHEMBL2584845 | 0.88 | LMNA (0.33) | SLC29A1LMNAALDH1A1 | |
| SCHEMBL2577912 | 0.86 | DNMT1 (0.37) | DNMT1ADRB1TLR7ALBDNMT3B | |
| SCHEMBL7240941 | 0.86 | DNMT1 (0.37) | DNMT1ADRB1TLR7ALBDNMT3B | |
| SCHEMBL2577913 | 0.86 | DNMT1 (0.37) | DNMT1ADRB1TLR7ALBDNMT3B | |
| SCHEMBL2583871 | 0.85 | DNMT1 (0.38) | DNMT1ADRB1TLR7ALBDNMT3B | |
| SCHEMBL2583868 | 0.85 | DNMT1 (0.38) | DNMT1ADRB1TLR7ALBDNMT3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |