Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | CASP1 | P29466 | 3/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663471 | 0.86 | MAPT (0.45) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1662862 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1663326 | 0.83 | ALDH1A1 (0.41) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1662749 | 0.82 | ALDH1A1 (0.40) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1662801 | 0.82 | ALDH1A1 (0.40) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1664938 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1662869 | 0.81 | ALDH1A1 (0.39) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1662501 | 0.80 | HPGD (0.42) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1663476 | 0.78 | ALDH1A1 (0.37) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1663504 | 0.75 | ALDH1A1 (0.36) | ALDH1A1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |