Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 3/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16632552 | 0.91 | HDAC8 (0.39) | ACACANPC1RAB9ALMNAMAPT | |
| SCHEMBL24471962 | 0.85 | ALOX5 (0.35) | PRKDCPIK3CDPIK3CALMNAKDM4E | |
| SCHEMBL16632670 | 0.84 | MERTK (0.33) | PRKDCPIK3CDPIK3CAACACAMAPT | |
| SCHEMBL16633166 | 0.84 | ABL1 (0.47) | ACACANPC1RAB9ALMNAMAPT | |
| SCHEMBL24370047 | 0.82 | ALOX5 (0.38) | PRKDCPIK3CDPIK3CALMNACRHR1 | |
| SCHEMBL17703153 | 0.82 | ALOX5 (0.38) | PRKDCPIK3CDPIK3CALMNACRHR1 | |
| SCHEMBL24472297 | 0.81 | ALOX5 (0.39) | PRKDCPIK3CDPIK3CALMNACRHR1 | |
| SCHEMBL26525040 | 0.81 | PRKDC (0.33) | PRKDCPIK3CDPIK3CALMNACRHR1 | |
| SCHEMBL22140592 | 0.81 | PRKDC (0.38) | PRKDCPIK3CDPIK3CALMNAPDCD1 | |
| SCHEMBL30501493 | 0.81 | ABL1 (0.47) | ACACANPC1RAB9ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9293712-B2 | Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same | UNIVERSAL DISPLAY CORPORATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-20150102321-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2015-04-16 | — | — | US | disclosed |