SCHEMBL16632702

SCHEMBL16632702

Ic1ccccc1C(c1ccccc1)c1ccccc1I

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 3/20 0.41
SLC6A4 P31645 3/20 0.41
SLC6A3 Q01959 3/20 0.41
CFTR P13569 1/20 0.37
GOPC Q9HD26 1/20 0.37
DPP4 P27487 2/20 0.36
F2 P00734 1/20 0.36
TSHR P16473 1/20 0.36
ALDH1A1 P00352 3/20 0.35
GAA P10253 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KMT2A Q03164 2/20 0.34
ATM Q13315 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
HTR2A P28223 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
IDO1 P14902 1/20 0.32
TDO2 P48775 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16632474 0.95 SLC6A2 (0.41) SLC6A2SLC6A4SLC6A3CFTRGOPC
SCHEMBL16632830 0.88 IDO1 (0.44) SLC6A2SLC6A4SLC6A3CFTRGOPC
SCHEMBL4088437 0.84 TAAR1 (0.33) SLC6A2SLC6A4SLC6A3TAAR1IDO1
Diethylamine SCHEMBL10776339 0.80 HTT (0.40) SLC6A2SLC6A4SLC6A3L3MBTL1KMT2A
SCHEMBL10779981 0.79 MEN1 (0.44) GAAKMT2ATDP1HDAC8HDAC6
SCHEMBL28888535 0.78 SLC6A2 (0.35) SLC6A2SLC6A4SLC6A3CFTRGOPC
SCHEMBL10778821 0.76 HPGD (0.53) SLC6A2TSHRALDH1A1GAAL3MBTL1
SCHEMBL30986671 0.76 MEN1 (0.48) SLC6A2SLC6A4SLC6A3TSHRGAA
SCHEMBL13714106 0.76 MEN1 (0.48) SLC6A2SLC6A4SLC6A3TSHRGAA
SCHEMBL8318669 0.76 TYR (0.46) ALDH1A1KMT2ATAAR1CYP2C9CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9815694-B2 Catalytic ammonia synthesis by transition metal molecular complexes CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2017-11-14 US disclosed
US-20150104371-A1 CATALYTIC AMMONIA SYNTHESIS BY TRANSITION METAL MOLECULAR COMPLEXES CALIFORNIA INSTITUTE OF TECHNOLOGY 2015-04-16 US disclosed