Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1233249 | 0.83 | MPO (0.49) | CYP1A2MAPTKMT2AGAATSHR | |
| SCHEMBL1234207 | 0.82 | MAPT (0.45) | CYP1A2MAPTKMT2AGAATSHR | |
| SCHEMBL15458737 | 0.81 | CYP1A2 (0.44) | CYP1A2MAPTKMT2AGAATSHR | |
| SCHEMBL1233602 | 0.80 | CYP1A2 (0.42) | CYP1A2MAPTKMT2AGAATSHR | |
| SCHEMBL1231889 | 0.77 | CNR2 (0.42) | CYP1A2MAPTKMT2AGAATP53 | |
| SCHEMBL22896893 | 0.76 | KMT2A (0.65) | MAPTKMT2AGAATP53POLB | |
| SCHEMBL7697931 | 0.75 | MPO (0.48) | CYP1A2MAPTKMT2AGAATP53 | |
| SCHEMBL22412805 | 0.74 | MAPT (0.44) | CYP1A2MAPTKMT2AGAATP53 | |
| SCHEMBL6778177 | 0.74 | MPO (0.47) | CYP1A2MAPTKMT2AGAATP53 | |
| SCHEMBL22412844 | 0.74 | MAPT (0.44) | CYP1A2MAPTKMT2AGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150105252-A1 | SUBSTITUTED PYRAZOLES AS HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105252-A1 | SUBSTITUTED PYRAZOLES AS HERBICIDES | CYP1B1, CYP1A1, DDT | CYP1A2 7/4885MAPT 4596/4885KMT2A 3783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.