SCHEMBL16632757

SCHEMBL16632757

CC(=O)N[C@H]1[C@H](OCc2ccccc2)O[C@H](COCc2ccccc2)[C@@H](O)[C@@H]1OCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SSTR5 P35346 6/20 0.52
SSTR3 P32745 5/20 0.52
SSTR4 P31391 4/20 0.52
SSTR2 P30874 3/20 0.52
SSTR1 P30872 1/20 0.52
POLB P06746 1/20 0.50
TP53 P04637 1/20 0.49
MDM2 Q00987 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.48
MCHR1 Q99705 7/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5841003 1.00 SSTR5 (0.52) SSTR5SSTR3SSTR4SSTR2SSTR1
SCHEMBL5840925 1.00 SSTR5 (0.52) SSTR5SSTR3SSTR4SSTR2SSTR1
SCHEMBL22053387 1.00 SSTR5 (0.52) SSTR5SSTR3SSTR4SSTR2SSTR1
SCHEMBL5840823 1.00 SSTR5 (0.52) SSTR5SSTR3SSTR4SSTR2SSTR1
SCHEMBL5840827 1.00 SSTR5 (0.52) SSTR5SSTR3SSTR4SSTR2SSTR1
SCHEMBL5841004 1.00 SSTR5 (0.52) SSTR5SSTR3SSTR4SSTR2SSTR1
SCHEMBL10525210 0.94 SSTR4 (0.51) SSTR5SSTR3SSTR4SSTR2SSTR1
SCHEMBL8894417 0.93 SSTR5 (0.54) SSTR5SSTR3SSTR4SSTR2SSTR1
SCHEMBL8894414 0.93 SSTR5 (0.54) SSTR5SSTR3SSTR4SSTR2SSTR1
SCHEMBL6760495 0.93 POLB (0.57) SSTR5SSTR3SSTR4SSTR2SSTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2852414-B9 MENINGOCOCCUS SEROGROUP X CONJUGATE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2020-12-09 EP disclosed
EP-2852414-B1 MENINGOCOCCUS SEROGROUP X CONJUGATE GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2020-07-08 EP disclosed
US-10668143-B2 Meningococcus serogroup X conjugate GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2020-06-02 US disclosed
US-10124051-B2 Meningococcus serogroup X conjugate GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2018-11-13 US disclosed
US-20150104479-A1 MENINGOCOCCUS SEROGROUP X CONJUGATE NOVARTIS AG (CH) 2015-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10668143-B2 Meningococcus serogroup X conjugate O60361, MLEC, PDHX SSTR5 4050/4885SSTR3 4726/4885SSTR4 4815/4885
US-20150104479-A1 MENINGOCOCCUS SEROGROUP X CONJUGATE O60361, MLEC, PDHX SSTR5 4050/4885SSTR3 4726/4885SSTR4 4815/4885
US-10124051-B2 Meningococcus serogroup X conjugate O60361, PDHX, MLEC SSTR5 4282/4885SSTR3 4777/4885SSTR4 4857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.