SCHEMBL6760495

SCHEMBL6760495

CC(=O)N[C@H]1[C@@H](OCc2ccccc2)O[C@H](COCc2ccccc2)[C@@H](O)[C@@H]1OC(C)=O

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.57
LMNA P02545 2/20 0.54
KMT2A Q03164 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.47
SSTR4 P31391 3/20 0.46
SSTR5 P35346 4/20 0.46
SSTR3 P32745 3/20 0.46
SSTR1 P30872 1/20 0.46
SSTR2 P30874 1/20 0.46
TP53 P04637 2/20 0.46
MDM2 Q00987 2/20 0.46
MAG P20916 1/20 0.44
NT5E P21589 1/20 0.43
MDM4 O15151 1/20 0.43
HSP90AA1 P07900 1/20 0.43
HSP90AB1 P08238 1/20 0.43
TACR1 P25103 1/20 0.43
TACR2 P21452 1/20 0.42
MCHR1 Q99705 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2503960 0.94 LMNA (0.58) POLBLMNAKMT2AL3MBTL1SSTR4
SCHEMBL2503954 0.94 LMNA (0.58) POLBLMNAKMT2AL3MBTL1SSTR4
SCHEMBL5841004 0.93 SSTR5 (0.52) POLBL3MBTL1SSTR4SSTR5SSTR3
SCHEMBL22053387 0.93 SSTR5 (0.52) POLBL3MBTL1SSTR4SSTR5SSTR3
SCHEMBL5840925 0.93 SSTR5 (0.52) POLBL3MBTL1SSTR4SSTR5SSTR3
SCHEMBL5841003 0.93 SSTR5 (0.52) POLBL3MBTL1SSTR4SSTR5SSTR3
SCHEMBL5840827 0.93 SSTR5 (0.52) POLBL3MBTL1SSTR4SSTR5SSTR3
SCHEMBL5840823 0.93 SSTR5 (0.52) POLBL3MBTL1SSTR4SSTR5SSTR3
SCHEMBL16632757 0.93 SSTR5 (0.52) POLBL3MBTL1SSTR4SSTR5SSTR3
SCHEMBL6760496 0.91 POLB (0.63) POLBLMNAKMT2AL3MBTL1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6723843-B2 USE OF A 2-SUBSTITUTED-1,3-DIOXOCYCLOALKYL LINKER GROUP TO COUPLE SACCHARIDE GROUPS OF BOTH THE O-GLYCOSIDE AND N-GLYCOSIDE TYPE TO A POLYMER SUPPORT IN A SOLID PHASE SYSTHESIS PROCESS ALCHEMIA PTY LTD (AU) 2004-04-20 US disclosed
US-6573337-B1 Dioxocyclohexane compound linker for solid-phase synthesis of oligosaccharides ALCHEMIA PTY LTD (AU) 2003-06-03 US disclosed
US-20030027925-A1 Oligosaccharide synthesis ALCHEMIA PTY LTD 2003-02-06 US disclosed
EP-0923528-B1 OLIGOSACCHARIDE SYNTHESIS ALCHEMIA PTY LTD (AU) 2002-11-06 EP disclosed