Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 2/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | PPP1CC | P36873 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663298 | 0.86 | PPM1B (0.37) | PPM1BPTPN1PPP1CCHCAR2NPSR1 | |
| SCHEMBL13881916 | 0.78 | — | — | |
| SCHEMBL14630771 | 0.70 | — | — | |
| SCHEMBL1583863 | 0.70 | — | — | |
| SCHEMBL1584181 | 0.70 | — | — | |
| SCHEMBL5135804 | 0.70 | — | — | |
| SCHEMBL1583972 | 0.70 | — | — | |
| SCHEMBL2685140 | 0.70 | — | — | |
| SCHEMBL5135807 | 0.70 | — | — | |
| SCHEMBL14630769 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |