Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 3/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | PPP1CC | P36873 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663302 | 0.86 | PPM1B (0.37) | PPM1BPTPN1PPP1CCHCAR2NPSR1 | |
| SCHEMBL20184262 | 0.80 | — | — | |
| SCHEMBL4412 | 0.78 | — | — | |
| Acetic Acid SCHEMBL28563384 | 0.76 | HCAR2 (0.47) | HCAR2MEN1ALDH1A1KMT2ANPSR1 | |
| SCHEMBL28285089 | 0.76 | — | — | |
| Alcohol SCHEMBL28357108 | 0.74 | HCAR2 (0.43) | HCAR2ALDH1A1NPSR1 | |
| Methylene Chloride SCHEMBL27697374 | 0.72 | HCAR2 (0.42) | HCAR2ALDH1A1HTTL3MBTL1NPSR1 | |
| Ethyl Acetate SCHEMBL10781172 | 0.71 | ALDH1A1 (0.56) | HCAR2ALDH1A1NPSR1 | |
| Ethylenediamine SCHEMBL15322398 | 0.71 | HCAR2 (0.41) | HCAR2ALDH1A1NPSR1 | |
| 1,2-Dichloroethane SCHEMBL28431339 | 0.71 | HCAR2 (0.41) | HCAR2ALDH1A1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |