Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 5/20 | 0.54 |
| ▸ | GGH | Q92820 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.42 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CPA3 | P15088 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12002454 | 1.00 | NAALAD2 (0.54) | NAALAD2GGHGAAMMP9MMP8 | |
| Arginine SCHEMBL1663212 | 0.82 | FOLH1 (0.39) | NAALAD2GGHGAAMMP9MMP8 | |
| Arginine SCHEMBL1662071 | 0.82 | FOLH1 (0.39) | NAALAD2GGHGAAMMP9MMP8 | |
| Arginine SCHEMBL12002430 | 0.82 | FOLH1 (0.39) | NAALAD2GGHGAAMMP9MMP8 | |
| Arginine SCHEMBL1660453 | 0.82 | FOLH1 (0.39) | NAALAD2GGHGAAMMP9MMP8 | |
| SCHEMBL20543567 | 0.80 | MME (0.51) | NAALAD2 | |
| SCHEMBL20543568 | 0.80 | MME (0.51) | NAALAD2 | |
| SCHEMBL7750537 | 0.80 | NAALAD2 (0.70) | NAALAD2GGHGAAMMP9MMP8 | |
| SCHEMBL19418994 | 0.80 | NAALAD2 (0.57) | NAALAD2GGHGAAMMP9MMP8 | |
| SCHEMBL11172440 | 0.78 | NAALAD2 (0.56) | NAALAD2GGHGAAMMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491051-A2 | GADD45BETA TARGETING AGENTS | Imperial Innovations Limited (GB) | 2012-08-29 | — | — | EP | claimed |
| WO-2011048390-A2 | GADD45BETA TARGETING AGENTS | IMPERIAL INNOVATIONS LIMITED (GB) | 2011-04-28 | — | — | WO | claimed |