SCHEMBL1663372

SCHEMBL1663372

O=C(O)c1ccc(C2CNCCO2)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29034228 0.86
SCHEMBL27585970 0.86
SCHEMBL27551455 0.86 SLC6A3 (0.59)
SCHEMBL13505593 0.86
SCHEMBL4034565 0.86 TAAR1 (0.55)
Hydrochloric Acid SCHEMBL13505419 0.84
SCHEMBL31385851 0.82
SCHEMBL27805833 0.82
SCHEMBL28561245 0.82
Water SCHEMBL27661766 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
US-20050010045-A1 Reacting morpholine compound with a substituted benzene compound TIAN WEI (SE) 2005-01-13 US claimed
US-6689882-B2 REACTING A MORPHOLINE WITH A SUBSTITUTED BENZENE, WHEREIN MORPHOLINE IS USED AS A REACTANT AND AS THE ONLY ONE SOLVENT ASTRAZENECA AB (SE) 2004-02-10 US claimed
US-20030171581-A1 Process for the synthesis of morpholinylbenzenes ASTRAZENECA AB (SE) 2003-09-11 US claimed
CN-1429216-A A new process for synthesis of morpholinylbenzenes ASTRAZENECA AB (SE) 2003-07-09 CN claimed
EP-1286977-A1 A NEW PROCESS FOR THE SYNTHESIS OF MORPHOLINYLBENZENES AstraZeneca AB (SE) 2003-03-05 EP claimed
WO-2001087865-A1 A NEW PROCESS FOR THE SYNTHESIS OF MORPHOLINYLBENZENES ASTRAZENECA AB (SE) 2001-11-22 WO claimed
CN-120192315-A Echinococcosis-resistant medicine and preparation method and application thereof 新疆医科大学 2025-06-24 CN disclosed
CN-118908915-A Cyclopropylamine compound, preparation method thereof and application thereof in antiviral aspect 中国医学科学院医药生物技术研究所 2024-11-08 CN disclosed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN disclosed
CN-118005638-A Pyrazolo [3,4-d ] pyrimidine structure-containing compound, and preparation method and application thereof 西安新通药物研究股份有限公司 2024-05-10 CN disclosed
CN-117682973-A Sulfonamide compound and medical application thereof 中国药科大学 2024-03-12 CN disclosed
CN-116535365-A Macrocyclic diamine derivatives and their combination with adenosine receptor antagonists as ENT inhibitors for the treatment of cancer ITEOS比利时公司 2023-08-04 CN disclosed
EP-2642994-A2 USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS Ligand Pharmaceuticals Incorporated (US) 2013-10-02 EP disclosed
US-20120295904-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES LIGAND PHARMACEUTICALS INC. (US) 2012-11-22 US disclosed
EP-2488486-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES Ligand Pharmaceuticals Inc. (US) 2012-08-22 EP disclosed
WO-2012068406-A2 USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS LIGAND PHARMACEUTICALS INCORPORATED (US) 2012-05-24 WO disclosed
WO-2011046954-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES LIGAND PHARMACEUTICALS INC. (US) 2011-04-21 WO disclosed
CN-1751025-A Diamine derivatives DAIICHI SEIYAKU CO (JP) 2006-03-22 CN disclosed
CN-1271279-A Amide derivatives for the treatment of diseases mediated by cytokines ZENECA LTD (GB) 2000-10-25 CN disclosed