Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31687256 | 0.83 | TDP1 (0.43) | PAOXTDP1KDM1AHPGDDUSP3 | |
| SCHEMBL30998792 | 0.83 | TDP1 (0.46) | PAOXTDP1KDM1AHPGDDUSP3 | |
| SCHEMBL4401738 | 0.78 | CA12 (0.53) | PAOXTDP1KDM1AHPGDDUSP3 | |
| SCHEMBL13912969 | 0.78 | PAOX (0.51) | PAOXKDM1AHPGDDUSP3CA12 | |
| SCHEMBL20332798 | 0.77 | TDP1 (0.56) | PAOXTDP1KDM1AHPGDDUSP3 | |
| SCHEMBL18995662 | 0.75 | PAOX (0.56) | PAOXKDM1AHPGDDUSP3CA12 | |
| SCHEMBL7326838 | 0.75 | PAOX (0.56) | PAOXKDM1AHPGDDUSP3CA12 | |
| SCHEMBL14805807 | 0.75 | PAOX (0.49) | PAOXTDP1KDM1AHPGDDUSP3 | |
| SCHEMBL18513274 | 0.75 | PAOX (0.56) | PAOXKDM1AHPGDDUSP3CA12 | |
| SCHEMBL26941306 | 0.75 | PAOX (0.56) | PAOXKDM1AHPGDDUSP3CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9427698-B2 | Amino-siloxane composition and methods of using the same | GENERAL ELECTRIC COMPANY (US) | 2016-08-30 | — | — | US | disclosed |
| US-20150104366-A1 | AMINO-SILOXANE COMPOSITION AND METHODS OF USING THE SAME | GENERAL ELECTRIC COMPANY (US) | 2015-04-16 | — | — | US | disclosed |