SCHEMBL30998792

SCHEMBL30998792

CO[Si](CCCNCCN1CCOCC1)(OC)OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.46
PAOX Q6QHF9 1/20 0.44
KDM1A O60341 1/20 0.42
HPGD P15428 1/20 0.41
DUSP3 P51452 1/20 0.41
ALDH1A1 P00352 2/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
CYP2C19 P33261 2/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
LMNA P02545 1/20 0.40
KDM4E B2RXH2 1/20 0.40
TP53 P04637 1/20 0.40
POLB P06746 1/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31687256 0.94 TDP1 (0.43) TDP1PAOXKDM1AHPGDDUSP3
SCHEMBL125043 0.83 SMN1; SMN2 (0.48) TDP1HPGDDUSP3ALDH1A1CYP2D6
SCHEMBL16634377 0.83 PAOX (0.46) TDP1PAOXKDM1AHPGDDUSP3
SCHEMBL2616713 0.82 TDP1 (0.55) TDP1ALDH1A1CYP2C19CYP2D6LMNA
SCHEMBL9420756 0.81 MEN1 (0.44) ALDH1A1CYP3A4CYP2D6LMNAKDM4E
SCHEMBL12802541 0.79 TDP1 (0.44) TDP1HPGDDUSP3ALDH1A1CYP2D6
SCHEMBL20332798 0.79 TDP1 (0.56) TDP1PAOXKDM1AHPGDDUSP3
SCHEMBL9935441 0.79 TDP1 (0.33) TDP1PAOXHPGDDUSP3ALDH1A1
SCHEMBL2616716 0.77 TDP1 (0.49) TDP1HPGDDUSP3ALDH1A1CYP2D6
SCHEMBL4401738 0.77 CA12 (0.53) TDP1PAOXKDM1AHPGDDUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240425531-A1 METHOD FOR PRODUCING CYCLIC SILAZANE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-12-26 US disclosed
EP-4410797-A1 METHOD FOR PRODUCING CYCLIC SILAZANE COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-08-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240425531-A1 METHOD FOR PRODUCING CYCLIC SILAZANE COMPOUND CCNE1, CCNE2, CCNT1 TDP1 4771/4885PAOX 4770/4885KDM1A 1071/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.