Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 3/20 | 0.71 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.71 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.71 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | CASP7 | P55210 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ASPH | Q12797 | 1/20 | 0.54 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634678 | 1.00 | MAPK13 (0.71) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL6657882 | 0.89 | MAPK13 (0.73) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL3301543 | 0.85 | KMT2A (0.61) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL13874222 | 0.84 | ALDH1A1 (0.57) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL6654262 | 0.84 | MAPK13 (0.71) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL7192087 | 0.84 | MAPK13 (0.78) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL6655015 | 0.83 | MAPK14 (1.00) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL7196619 | 0.83 | MAPK13 (0.76) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL2199203 | 0.83 | MAPK13 (0.77) | MAPK13MAPK12MAPK11MAPK14MEN1 | |
| SCHEMBL6655495 | 0.82 | MAPK14 (0.82) | MAPK13MAPK12MAPK11MAPK14MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015052675-A1 | SUBSTITUTED DIHYDRO-BENZIMIDAZOLE COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-04-16 | — | — | WO | disclosed |