Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 6/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.47 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664498 | 0.96 | MAOB (0.58) | MAOBMAPK10MAPK8MAPTALDH1A1 | |
| SCHEMBL1663507 | 0.96 | MAOB (0.56) | MAOBMAPK10MAPK8MAPTALDH1A1 | |
| SCHEMBL1666113 | 0.92 | MAOB (0.52) | MAOBMAPK10MAPK8MAPTALDH1A1 | |
| SCHEMBL1664500 | 0.92 | MAOB (0.63) | MAOBMAPK10MAPK8MAPTALDH1A1 | |
| SCHEMBL13836343 | 0.92 | MAOB (0.55) | MAOBMAPK10MAPK8MAPTALDH1A1 | |
| SCHEMBL1666595 | 0.92 | MAOB (0.52) | MAOBMAPK10MAPK8MAPTALDH1A1 | |
| SCHEMBL1666192 | 0.89 | MAOB (0.46) | MAOBMAPK10MAPK8MAPTALDH1A1 | |
| SCHEMBL1663170 | 0.88 | MAPT (0.53) | MAOBMAPTALDH1A1MAPK1NPC1 | |
| SCHEMBL1665686 | 0.87 | MAOB (0.48) | MAOBMAPK10MAPK8MAPTALDH1A1 | |
| SCHEMBL1667338 | 0.87 | MAOB (0.48) | MAOBMAPK10MAPK8MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2642994-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | Ligand Pharmaceuticals Incorporated (US) | 2013-10-02 | — | — | EP | disclosed |
| EP-2488486-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | Ligand Pharmaceuticals Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2012068406-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2012-05-24 | — | — | WO | disclosed |
| WO-2011046954-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2011-04-21 | — | — | WO | disclosed |