Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMO | Q99835 | 9/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13836343 | 0.89 | MAOB (0.55) | MAOBMAPK10MAPK8NPC1RAB9A | |
| SCHEMBL1663505 | 0.89 | MAOB (0.54) | MAOBMAPK10MAPK8NPC1RAB9A | |
| SCHEMBL1664498 | 0.87 | MAOB (0.58) | MAOBMAPK10MAPK8NPC1RAB9A | |
| SCHEMBL1663507 | 0.84 | MAOB (0.56) | MAOBMAPK10MAPK8NPC1RAB9A | |
| SCHEMBL1664500 | 0.83 | MAOB (0.63) | MAOBMAPK10MAPK8NPC1RAB9A | |
| SCHEMBL1666595 | 0.81 | MAOB (0.52) | MAOBMAPK10MAPK8NPC1RAB9A | |
| SCHEMBL1666113 | 0.81 | MAOB (0.52) | MAOBMAPK10MAPK8NPC1RAB9A | |
| SCHEMBL1663170 | 0.77 | MAPT (0.53) | MAOBNPC1RAB9AALDH1A1MAPT | |
| SCHEMBL1665686 | 0.77 | MAOB (0.48) | MAOBMAPK10MAPK8NPC1RAB9A | |
| SCHEMBL1667338 | 0.77 | MAOB (0.48) | MAOBMAPK10MAPK8NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2642994-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | Ligand Pharmaceuticals Incorporated (US) | 2013-10-02 | — | — | EP | disclosed |
| EP-2488486-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | Ligand Pharmaceuticals Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2012068406-A2 | USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2012-05-24 | — | — | WO | disclosed |
| WO-2011046954-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2011-04-21 | — | — | WO | disclosed |