Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.59 |
| ▸ | PPARA | Q07869 | 17/20 | 0.59 |
| ▸ | PPARD | Q03181 | 3/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27821524 | 1.00 | PPARG (0.59) | PPARGPPARAPPARDTRPM8SIGMAR1 | |
| SCHEMBL30613915 | 1.00 | PPARG (0.59) | PPARGPPARAPPARDTRPM8SIGMAR1 | |
| SCHEMBL3380544 | 0.84 | PPARA (0.44) | PPARGPPARAPPARD | |
| SCHEMBL7420613 | 0.84 | PPARA (0.44) | PPARGPPARAPPARD | |
| SCHEMBL10708009 | 0.81 | PPARG (0.50) | PPARGPPARAPPARD | |
| SCHEMBL6791705 | 0.81 | PPARG (0.58) | PPARGPPARAPPARD | |
| SCHEMBL10324581 | 0.80 | PPARG (0.56) | PPARGPPARAPPARDTRPM8 | |
| SCHEMBL6798234 | 0.78 | PPARG (0.72) | PPARGPPARAPPARD | |
| SCHEMBL8426777 | 0.77 | TRPM8 (0.42) | PPARGPPARATRPM8SIGMAR1 | |
| SCHEMBL3519974 | 0.76 | TRPM8 (0.47) | PPARGPPARAPPARDTRPM8SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024146868-A1 | COMPOSITIONS FOR HORMONALLY IMPACTED SKIN | THE BOOTS COMPANY PLC (GB) | 2024-07-11 | — | — | WO | disclosed |
| WO-2023071973-A1 | FUSED BICYCLIC COMPOUND FOR INHIBITING ACTIVITY OF TYROSINE KINASE | SHENZHEN TARGETRX, INC. (CN) | 2023-05-04 | — | — | WO | disclosed |
| WO-2020162612-A1 | PYRIDINE COMPOUND SUBSTITUTED BY HETEROARYL | 大正製薬株式会社 | 2020-08-13 | — | — | WO | disclosed |
| WO-2016192074-A1 | BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-12-08 | — | — | WO | disclosed |
| WO-2016161571-A1 | INDAZOLE AND AZAINDAZOLE BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-10-13 | — | — | WO | disclosed |
| WO-2016106629-A1 | BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016106625-A1 | BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016106628-A1 | BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016106624-A1 | TERTIARY ALCOHOL IMIDAZOPYRAZINE BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016106623-A1 | BENZAMIDE IMIDAZOPYRAZINE BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016106627-A1 | BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016106626-A1 | IMIDAZOPYRAZINE ANALOGS WITH 3-TERTIARY CARBON SUBSTITUTIONS AS BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016106652-A1 | BIARYLETHER IMIDAZOPYRAZINE BTK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-07-07 | — | — | WO | disclosed |
| WO-2016095088-A1 | ERK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-06-23 | — | — | WO | disclosed |
| WO-2015051766-A1 | AMIDS SUBSTITUTED INDAZOLE DERIVATIVEES AS PLOY (ADP-RIBOSE) POLYMERASE INHIBITORS | BETTA PHARMACEUTICALS CO., LTD (CN) | 2015-04-16 | — | — | WO | disclosed |
| CN-101133024-A | Amide derivatives as histone deacetylase inhibitors | ANGELETTI P IST RICHERCHE BIO (IT) | 2008-02-27 | — | — | CN | disclosed |
| CN-1980911-A | Mitotic kinesin inhibitors | MERCK & CO INC (US) | 2007-06-13 | — | — | CN | disclosed |