Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662624 | 0.86 | MAPT (0.43) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL1664501 | 0.82 | MAPT (0.39) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL1663125 | 0.82 | ALDH1A1 (0.40) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL1663187 | 0.77 | MAPT (0.40) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL1662820 | 0.74 | KDM4E (0.43) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL26651257 | 0.72 | KDM4E (0.36) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL1664819 | 0.69 | F2 (0.37) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL1662907 | 0.68 | ALDH1A1 (0.48) | MAPTKDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL1663480 | 0.67 | MAPT (0.43) | MAPTKDM4EALDH1A1HSD17B10CASP1 | |
| SCHEMBL18372562 | 0.64 | MRGPRX4 (0.36) | MAPTKDM4EALDH1A1SMN1; SMN2MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |