SCHEMBL16636359

SCHEMBL16636359

C=CCOCC=C.O=C(O)CCCCCCCCCCCCCCO

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 5/20 0.61
FFAR1 O14842 2/20 0.61
FFAR4 Q5NUL3 2/20 0.61
ABCC4 O15439 1/20 0.53
MAPT P10636 1/20 0.53
CAMK2A Q9UQM7 1/20 0.48
TSHR P16473 6/20 0.46
LMNA P02545 3/20 0.46
NFKB1 P19838 1/20 0.46
PMP22 Q01453 1/20 0.46
FNTA P49354 1/20 0.40
FNTB P49356 1/20 0.40
ALDH1A1 P00352 4/20 0.39
PPARG P37231 6/20 0.39
PPARD Q03181 6/20 0.39
PPARA Q07869 6/20 0.39
HDAC11 Q96DB2 5/20 0.39
TLR2 O60603 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
MEN1 O00255 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16635954 1.00 GPR84 (0.61) GPR84FFAR1FFAR4ABCC4MAPT
Adipic Acid SCHEMBL7135978 0.90 ABCC4 (0.58) GPR84FFAR1FFAR4ABCC4MAPT
Stearic Acid SCHEMBL6408644 0.86 GPR84 (0.57) GPR84FFAR1FFAR4MAPTTSHR
Adipic Acid SCHEMBL3224275 0.85 ABCC4 (0.48) GPR84FFAR1FFAR4ABCC4MAPT
Adipic Acid SCHEMBL27803366 0.84 ABCC4 (0.52) GPR84FFAR1FFAR4ABCC4MAPT
SCHEMBL472093 0.83 CA1 (0.38) GPR84FFAR1FFAR4TSHRLMNA
SCHEMBL6600382 0.83 CA1 (0.38) GPR84FFAR1FFAR4TSHRLMNA
1,5-Pentanediol SCHEMBL472091 0.83 CA1 (0.38) GPR84FFAR1FFAR4TSHRLMNA
1,6-Hexanediol SCHEMBL472147 0.83 CA1 (0.38) GPR84FFAR1FFAR4TSHRLMNA
SCHEMBL472068 0.83 CA1 (0.38) GPR84FFAR1FFAR4TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105814127-B Reactive functional group silicone composition 迈图高新材料股份有限公司 2019-07-26 CN disclosed
EP-3036279-B1 REACTIVE FUNCTIONAL SILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MAT GMBH (DE) 2019-05-08 EP disclosed
US-9771458-B2 Reactive functional siloxane compositions MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2017-09-26 US disclosed
US-20160251483-A1 Reactive Functional Siloxane Compositions MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2016-09-01 US disclosed
CN-105814127-A Reactive functional siloxane compositions 迈图高新材料股份有限公司 2016-07-27 CN disclosed
EP-3036279-A1 REACTIVE FUNCTIONAL SILOXANE COMPOSITIONS Momentive Performance Materials GmbH (DE) 2016-06-29 EP disclosed
WO-2015052229-A1 REACTIVE FUNCTIONAL SILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2015-04-16 WO disclosed