Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126615 | 0.89 | LMNA (0.67) | LMNATHRB | |
| Phosphonic Acid SCHEMBL9815258 | 0.89 | LMNA (0.67) | LMNATHRB | |
| SCHEMBL6135761 | 0.86 | LMNA (0.63) | LMNATHRB | |
| Ethylene SCHEMBL10332980 | 0.86 | LMNA (0.63) | LMNATHRB | |
| Ethylene Glycol SCHEMBL1574049 | 0.84 | LMNA (0.55) | LMNATHRB | |
| Butane SCHEMBL6269157 | 0.84 | LMNA (0.60) | LMNATHRB | |
| Phosphoric Acid SCHEMBL7670890 | 0.83 | LMNA (0.52) | LMNATHRB | |
| Cyclopentane SCHEMBL9669110 | 0.82 | LMNA (0.57) | LMNATHRB | |
| SCHEMBL6387880 | 0.77 | LMNA (0.50) | LMNA | |
| Triethylene Glycol SCHEMBL4402974 | 0.76 | LMNA (0.44) | LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11970512-B2 | Amphotericin B derivatives with improved therapeutic index | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2024-04-30 | — | — | US | disclosed |
| CN-110407898-B | Amphotericin B derivatives with improved therapeutic index | 伊利诺伊大学评议会 | 2023-12-01 | — | — | CN | disclosed |
| US-20220056066-A1 | AMPHOTERICIN B DERIVATIVES WITH IMPROVED THERAPEUTIC INDEX | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2022-02-24 | — | — | US | disclosed |
| US-11117920-B2 | Amphotericin B derivatives with improved therapeutic index | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-09-14 | — | — | US | disclosed |
| US-11028114-B2 | Amphotericin B derivatives with improved therapeutic index | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2021-06-08 | — | — | US | disclosed |
| US-20190345187-A1 | AMPHOTERICIN B DERIVATIVES WITH IMPROVED THERAPEUTIC INDEX | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2019-11-14 | — | — | US | disclosed |
| US-10323057-B2 | Amphotericin B derivatives with improved therapeutic index | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2019-06-18 | — | — | US | disclosed |
| EP-3055030-B1 | AMPHOTERICIN B DERIVATIVES WITH IMPROVED THERAPEUTIC INDEX | UNIV ILLINOIS (US) | 2018-05-02 | — | — | EP | disclosed |
| EP-3055030-A1 | AMPHOTERICIN B DERIVATIVES WITH IMPROVED THERAPEUTIC INDEX | The Board of Trustees of the University of Illinois (US) | 2016-08-17 | — | — | EP | disclosed |
| US-20160215012-A1 | AMPHOTERICIN B DERIVATIVES WITH IMPROVED THERAPEUTIC INDEX | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (IL) | 2016-07-28 | — | — | US | disclosed |
| WO-2015054148-A1 | AMPHOTERICIN B DERIVATIVES WITH IMPROVED THERAPEUTIC INDEX | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-04-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220056066-A1 | AMPHOTERICIN B DERIVATIVES WITH IMPROVED THERAPEUTIC INDEX | C9, AMPD3, C5 | LMNA 280/4885THRB 4084/4885 |
| US-20160215012-A1 | AMPHOTERICIN B DERIVATIVES WITH IMPROVED THERAPEUTIC INDEX | C9, AMPD3, C5 | LMNA 280/4885THRB 4084/4885 |
| US-20190345187-A1 | AMPHOTERICIN B DERIVATIVES WITH IMPROVED THERAPEUTIC INDEX | C9, AMPD3, C5 | LMNA 280/4885THRB 4084/4885 |
| US-10323057-B2 | Amphotericin B derivatives with improved therapeutic index | C9, AMPD3, C5 | LMNA 280/4885THRB 4084/4885 |
| US-11028114-B2 | Amphotericin B derivatives with improved therapeutic index | C9, AMPD3, C5 | LMNA 280/4885THRB 4084/4885 |
| US-11117920-B2 | Amphotericin B derivatives with improved therapeutic index | C9, AMPD3, C5 | LMNA 280/4885THRB 4084/4885 |
| US-11970512-B2 | Amphotericin B derivatives with improved therapeutic index | C9, AMPD3, C5 | LMNA 280/4885THRB 4084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.