Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 10/20 | 0.55 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.45 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664160 | 1.00 | HPGDS (0.55) | HPGDSMCHR1PDE7A | |
| SCHEMBL8775621 | 0.95 | HPGDS (0.56) | HPGDSMCHR1 | |
| SCHEMBL6119181 | 0.95 | HPGDS (0.56) | HPGDSMCHR1 | |
| SCHEMBL1663665 | 0.95 | HPGDS (0.56) | HPGDSMCHR1 | |
| SCHEMBL1666281 | 0.95 | HPGDS (0.56) | HPGDSMCHR1 | |
| SCHEMBL1666278 | 0.95 | HPGDS (0.60) | HPGDSMCHR1PDE7A | |
| SCHEMBL1664351 | 0.94 | HPGDS (0.62) | HPGDSMCHR1 | |
| SCHEMBL1663295 | 0.89 | HPGDS (0.63) | HPGDSMCHR1 | |
| SCHEMBL1664354 | 0.89 | HPGDS (0.63) | HPGDSMCHR1 | |
| SCHEMBL6125839 | 0.85 | HPGDS (0.50) | HPGDSMCHR1PDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2488486-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | Ligand Pharmaceuticals Inc. (US) | 2012-08-22 | — | — | EP | disclosed |
| WO-2011046954-A1 | HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES | LIGAND PHARMACEUTICALS INC. (US) | 2011-04-21 | — | — | WO | disclosed |