Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 8/20 | 0.64 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.64 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.64 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.64 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.64 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.64 |
| ▸ | CES2 | O00748 | 1/20 | 0.64 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.64 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.60 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.54 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.54 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.54 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TSPO | P30536 | 1/20 | 0.54 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16395496 | 1.00 | LPAR1 (0.64) | LPAR1LPAR3ENPP2LPAR2LPAR4 | |
| SCHEMBL8744617 | 0.92 | ENPP2 (0.58) | LPAR1LPAR3ENPP2LPAR2LPAR4 | |
| SCHEMBL7739234 | 0.92 | ENPP2 (0.58) | LPAR1LPAR3ENPP2LPAR2LPAR4 | |
| SCHEMBL6646106 | 0.86 | LPAR1 (0.60) | LPAR1LPAR3ENPP2LPAR2LPAR4 | |
| SCHEMBL18628314 | 0.84 | LPAR1 (0.65) | LPAR1LPAR3ENPP2LPAR2LPAR4 | |
| SCHEMBL28281769 | 0.84 | LPAR1 (0.65) | LPAR1LPAR3ENPP2LPAR2LPAR4 | |
| SCHEMBL4979203 | 0.84 | LPAR1 (0.63) | LPAR1LPAR3ENPP2LPAR2LPAR4 | |
| Phosphoric Acid SCHEMBL28539599 | 0.82 | FABP3 (0.51) | — | |
| Alcohol SCHEMBL28250193 | 0.82 | S1PR1 (0.63) | LPAR1LPAR3ENPP2LPAR2LPAR4 | |
| SCHEMBL8776459 | 0.81 | S1PR4 (0.59) | LPAR1LPAR3ENPP2LPAR2LPAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3065732-A1 | COMPOUNDS, COMPOSITIONS AND USES THEREOF FOR THE PREVENTION AND/OR TREATMENT OF DYSLIPIDEMIA | Centre National de la Recherche Scientifique (CNRS) (FR) | 2016-09-14 | — | — | EP | claimed |
| WO-2015052237-A1 | COMPOUNDS, COMPOSITIONS AND USES THEREOF FOR THE PREVENTION AND/OR TREATMENT OF DYSLIPIDEMIA | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2015-04-16 | — | — | WO | claimed |
| EP-3065733-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING SUCH COMPOUNDS FOR THE PREVENTION OR TREATMENT OF DYSLIPIDAEMIAS | Centre National De La Recherche Scientifique (FR) | 2016-09-14 | — | — | EP | disclosed |
| EP-3065732-A1 | COMPOUNDS, COMPOSITIONS AND USES THEREOF FOR THE PREVENTION AND/OR TREATMENT OF DYSLIPIDEMIA | Centre National de la Recherche Scientifique (CNRS) (FR) | 2016-09-14 | — | — | EP | disclosed |
| WO-2015052433-A1 | COMPOUNDS AND COMPOSITIONS COMPRISING SUCH COMPOUNDS FOR THE PREVENTION OR TREATMENT OF DYSLIPIDAEMIAS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2015-04-16 | — | — | WO | disclosed |
| WO-2015052237-A1 | COMPOUNDS, COMPOSITIONS AND USES THEREOF FOR THE PREVENTION AND/OR TREATMENT OF DYSLIPIDEMIA | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2015-04-16 | — | — | WO | disclosed |