SCHEMBL16637074

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30295133	0.89	LRRK2 (0.61)	LRRK2CNR2CNR1KITBTK
	SCHEMBL29247128	0.89	LRRK2 (0.61)	LRRK2CNR2CNR1KITBTK
	SCHEMBL30295134	0.89	LRRK2 (0.61)	LRRK2CNR2CNR1KITBTK
	SCHEMBL28367334	0.87	AKT1 (0.55)	CNR2CNR1KITBTKAKT1
	SCHEMBL29247486	0.85	KIT (0.55)	LRRK2CNR2CNR1KITBTK
	SCHEMBL30372597	0.85	KIT (0.55)	LRRK2CNR2CNR1KITBTK
	SCHEMBL28129919	0.85	LRRK2 (0.61)	LRRK2CNR2KITSTK4STK3
	SCHEMBL16636776	0.82	LRRK2 (0.66)	LRRK2CNR2KITSTK4STK3
	SCHEMBL28367843	0.81	AKT1 (0.57)	KITBTKAKT1AKT1S1
	SCHEMBL2253309	0.81	AKT1 (0.57)	KITBTKAKT1AKT1S1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.