SCHEMBL16637135

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16647170	0.90	TLR9 (0.49)	TLR9CNR1CNR2GBA1DPP4
	SCHEMBL28450955	0.89	TLR9 (0.47)	TLR9CNR1CNR2GBA1DPP4
	SCHEMBL16637261	0.88	TLR9 (0.51)	TLR9CNR1CNR2GBA1DPP4
	SCHEMBL21415473	0.86	PRKAB2 (0.49)	PDE4APDE4BPDE4CPDE4DHRH4
	SCHEMBL16637099	0.85	KIT (0.53)	CNR1CNR2KITADKMEN1
	SCHEMBL29765709	0.85	KIT (0.53)	CNR1CNR2KITADKMEN1
	SCHEMBL16636895	0.84	TLR9 (0.49)	TLR9GBA1KITMEN1KMT2A
	SCHEMBL29765995	0.83	KRAS (0.49)	—
	SCHEMBL16636765	0.83	KRAS (0.49)	—
	SCHEMBL16637134	0.78	HRH4 (0.39)	CNR1CNR2PDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.