SCHEMBL16637153

SCHEMBL16637153

O=C(O)C(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.64

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.64
CA2 P00918 9/20 0.33
CA1 P00915 8/20 0.33
MMP1 P03956 2/20 0.33
MMP2 P08253 2/20 0.33
MMP9 P14780 2/20 0.33
MMP8 P22894 2/20 0.33
MMP13 P45452 2/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.31
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9139267 1.00 THRB (0.64) THRBCA2CA1MMP1MMP2
SCHEMBL1501589 1.00 THRB (0.64) THRBCA2CA1MMP1MMP2
Ammonia Solution, Strong SCHEMBL1501477 0.97 THRB (0.61) THRBCA2CA1MMP1MMP2
SCHEMBL1079403 0.97 THRB (0.59) THRBCA2CA1MMP1MMP2
SCHEMBL1079202 0.89 THRB (0.48) THRB
Silver SCHEMBL30466764 0.83 THRB (0.62) THRBCA2CA1MMP1MMP2
SCHEMBL2401754 0.81 THRB (0.67) THRBCA2CA1MMP1MMP2
SCHEMBL12095169 0.81 THRB (0.67) THRBCA2CA1MMP1MMP2
SCHEMBL2401748 0.81 THRB (0.67) THRBCA2CA1MMP1MMP2
SCHEMBL4341497 0.81 THRB (0.67) THRBCA2CA1MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9051510-B1 Treatment fluids containing a perfluorinated carboxylic acid for use in subterranean formation operations HALLIBURTON ENERGY SERVICES, INC. (US) 2015-06-09 US claimed
WO-2015053817-A1 TREATMENT FLUIDS CONTAINING A PERFLUORINATED CARBOXYLIC ACID FOR USE IN SUBTERRANEAN FORMATION OPERATIONS HALLIBURTON ENERGY SERVICES, INC. (US) 2015-04-16 WO claimed
US-9051510-B1 Treatment fluids containing a perfluorinated carboxylic acid for use in subterranean formation operations HALLIBURTON ENERGY SERVICES, INC. (US) 2015-06-09 US disclosed
WO-2015053817-A1 TREATMENT FLUIDS CONTAINING A PERFLUORINATED CARBOXYLIC ACID FOR USE IN SUBTERRANEAN FORMATION OPERATIONS HALLIBURTON ENERGY SERVICES, INC. (US) 2015-04-16 WO disclosed