Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 14/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16637490 | 0.79 | HPGD (0.67) | HPGDALDH1A1TDP1GAAMEN1 | |
| SCHEMBL7132525 | 0.70 | HPGD (1.00) | HPGDALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL27479149 | 0.70 | HPGD (1.00) | HPGDALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL10721733 | 0.68 | HPGD (0.95) | HPGDALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL4491431 | 0.67 | HPGD (0.83) | HPGDALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL4050706 | 0.67 | HPGD (0.83) | HPGDALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL3917299 | 0.67 | HPGD (0.83) | HPGDALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL11112400 | 0.66 | HPGD (0.80) | HPGDALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL3455787 | 0.66 | HPGD (0.80) | HPGDALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL1590985 | 0.66 | HPGD (0.80) | HPGDALDH1A1MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051713-A1 | 4,5-DIHYDRO-PYRAZOLO[3,4-C]PYRIDIN-2-ONE SPIRO DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2015-04-16 | — | — | WO | disclosed |
| WO-2015051713-A1 | 4,5-DIHYDRO-PYRAZOLO[3,4-C]PYRIDIN-2-ONE SPIRO DERIVATIVE, PREPARATION METHOD AND USE THEREOF | 四川海思科制药有限公司 | 2015-04-16 | — | — | WO | disclosed |