SCHEMBL16637207

SCHEMBL16637207

Clc1nc(-c2cccc(-c3ccccc3)c2)nc(-c2ccc3oc4ccccc4c3c2)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 4/20 0.46
PLA2G4A P47712 4/20 0.46
PLA2G10 O15496 1/20 0.46
AHR P35869 2/20 0.44
MAPT P10636 3/20 0.41
MEN1 O00255 3/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 3/20 0.41
KMT2A Q03164 3/20 0.41
NPC1 O15118 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
KDM4E B2RXH2 1/20 0.41
RAB9A P51151 1/20 0.41
PIM1 P11309 1/20 0.40
CSNK2A2 P19784 1/20 0.40
CSNK2B P67870 1/20 0.40
PIM3 Q86V86 1/20 0.40
PIM2 Q9P1W9 1/20 0.40
CHEK2 O96017 1/20 0.40
GAA P10253 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31590787 1.00 PLA2G2A (0.46) PLA2G2APLA2G4APLA2G10AHRMAPT
SCHEMBL29632998 0.97 PLA2G2A (0.46) PLA2G2APLA2G4APLA2G10AHRMAPT
SCHEMBL23437192 0.97 PLA2G2A (0.46) PLA2G2APLA2G4APLA2G10AHRMAPT
SCHEMBL25818435 0.96 PLA2G2A (0.43) PLA2G2APLA2G4APLA2G10AHRMAPT
SCHEMBL22161545 0.96 PLA2G2A (0.46) PLA2G2APLA2G4APLA2G10AHRMAPT
SCHEMBL25132310 0.96 PLA2G2A (0.43) PLA2G2APLA2G4APLA2G10AHRMAPT
SCHEMBL25818439 0.95 PLA2G2A (0.42) PLA2G2APLA2G4APLA2G10AHRMAPT
SCHEMBL25132306 0.94 PLA2G2A (0.42) PLA2G2APLA2G4APLA2G10MAPTMEN1
SCHEMBL22161548 0.94 AHR (0.46) PLA2G2APLA2G4APLA2G10AHRMAPT
SCHEMBL30477730 0.94 AHR (0.46) PLA2G2APLA2G4APLA2G10AHRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4190880-A1 COMPOUNDS USABLE AS ACTIVE COMPOUNDS IN AN ORGANIC ELECTRONIC DEVICE Merck Patent GmbH (DE) 2023-06-07 EP disclosed
EP-3856868-B1 COMPOUNDS THAT CAN BE USED IN AN ORGANIC ELECTRONIC DEVICE AS ACTIVE COMPOUNDS MERCK PATENT GMBH (DE) 2023-01-25 EP disclosed
US-20210384443-A1 COMPOUNDS THAT CAN BE USED IN AN ORGANIC ELECTRONIC DEVICE AS ACTIVE COMPOUNDS MERCK PATENT GMBH (DE) 2021-12-09 US disclosed
WO-2019143109-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 주식회사 두산 2019-07-25 WO disclosed
WO-2019143109-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 주식회사 두산 2019-07-25 WO disclosed
WO-2015053524-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING SAME 주식회사 두산 2015-04-16 WO disclosed