SCHEMBL16637323

SCHEMBL16637323

Clc1nc(-c2cccc3ccccc23)nc(-c2cccc3c2oc2ccccc23)n1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.43
ALDH1A1 P00352 5/20 0.43
HSD17B10 Q99714 5/20 0.43
KDM4E B2RXH2 4/20 0.43
MAPT P10636 4/20 0.43
HPGD P15428 4/20 0.43
GAA P10253 1/20 0.43
PRKDC P78527 2/20 0.40
PIK3CD O00329 1/20 0.40
PIK3CB P42338 1/20 0.40
SMN1; SMN2 Q16637 3/20 0.39
TP53 P04637 2/20 0.39
MAPK1 P28482 2/20 0.39
NPC1 O15118 1/20 0.39
AHR P35869 3/20 0.39
PIM1 P11309 1/20 0.38
CSNK2A2 P19784 1/20 0.38
CSNK2B P67870 1/20 0.38
PIM3 Q86V86 1/20 0.38
PIM2 Q9P1W9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29633038 1.00 ALOX5 (0.43) ALOX5ALDH1A1HSD17B10KDM4EMAPT
SCHEMBL16637130 0.94 ALOX5 (0.48) ALOX5ALDH1A1HSD17B10KDM4EMAPT
SCHEMBL26435827 0.92 ALOX5 (0.45) ALOX5ALDH1A1HSD17B10KDM4EMAPT
SCHEMBL25437788 0.91 ALOX5 (0.48) ALOX5ALDH1A1HSD17B10KDM4EMAPT
SCHEMBL17470491 0.91 ALOX5 (0.48) ALOX5ALDH1A1HSD17B10KDM4EMAPT
SCHEMBL29550976 0.91 ALOX5 (0.48) ALOX5ALDH1A1HSD17B10KDM4EMAPT
SCHEMBL22889415 0.90 ALOX5 (0.50) ALOX5ALDH1A1HSD17B10KDM4EMAPT
SCHEMBL16636998 0.87 ALOX5 (0.45) ALOX5ALDH1A1HSD17B10KDM4EMAPT
SCHEMBL29603481 0.87 ALOX5 (0.45) ALOX5ALDH1A1HSD17B10KDM4EMAPT
SCHEMBL26448564 0.87 ALOX5 (0.45) ALOX5ALDH1A1HSD17B10KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022103109-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 솔루스첨단소재 주식회사 2022-05-19 WO disclosed
WO-2015053524-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING SAME 주식회사 두산 2015-04-16 WO disclosed