Ethylene Glycol

Ethylene Glycol

SCHEMBL16637379

C=C(C)C(=O)OCCN(C)C.OCCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.48
CHRM2 P08172 1/20 0.48
CHRM4 P08173 1/20 0.48
CHRM5 P08912 1/20 0.48
CHRM1 P11229 1/20 0.48
CHRNB2 P17787 1/20 0.48
CHRM3 P20309 1/20 0.48
CHRNA4 P43681 1/20 0.48
TSHR P16473 3/20 0.47
DNM1 Q05193 1/20 0.40
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
BCHE P06276 1/20 0.38
ALDH1A1 P00352 4/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
PHLPP2 Q6ZVD8 1/20 0.38
POLB P06746 1/20 0.36
APEX1 P27695 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2414790 0.94 THRB (0.47) THRBCHRM2CHRM4CHRM5CHRM1
SCHEMBL28671752 0.94 CHRM2 (0.54) THRBCHRM2CHRM4CHRM5CHRM1
SCHEMBL14984 0.94 CHRM2 (0.54) THRBCHRM2CHRM4CHRM5CHRM1
SCHEMBL11650326 0.92 CHRM2 (0.52) THRBCHRM2CHRM4CHRM5CHRM1
Fluoride SCHEMBL1255040 0.92 CHRM2 (0.52) THRBCHRM2CHRM4CHRM5CHRM1
Ammonia Solution, Strong SCHEMBL8139148 0.92 CHRM2 (0.52) THRBCHRM2CHRM4CHRM5CHRM1
Iodide SCHEMBL1254951 0.92 CHRM2 (0.52) THRBCHRM2CHRM4CHRM5CHRM1
Bromide SCHEMBL1255341 0.92 CHRM2 (0.52) THRBCHRM2CHRM4CHRM5CHRM1
Methyl Alcohol SCHEMBL21326731 0.92 CHRM2 (0.52) THRBCHRM2CHRM4CHRM5CHRM1
Hydrochloric Acid SCHEMBL129149 0.92 CHRM2 (0.52) THRBCHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015053716-A1 DIRECT SYNTHESIS OF PH-RESPONSIVE POLYMER PARTICLES AND APPLICATION IN CONTROL RELEASE OF HYDROPHOBIC THERAPEUTIC COMPOUNDS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2015-04-16 WO disclosed