Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471771 | 0.96 | TSHR (0.35) | TSHRTDP1MEN1LMNACYP3A4 | |
| SCHEMBL1471883 | 0.94 | TSHR (0.32) | TSHRALDH1A1 | |
| SCHEMBL1469499 | 0.93 | ALDH1A1 (0.46) | TSHRTDP1LMNACYP3A4ALDH1A1 | |
| SCHEMBL12262428 | 0.89 | TSHR (0.30) | TSHR | |
| SCHEMBL1470238 | 0.88 | ALDH1A1 (0.40) | TSHRTDP1LMNAALDH1A1 | |
| SCHEMBL1470369 | 0.87 | TSHR (0.42) | TSHRTDP1ALDH1A1 | |
| SCHEMBL1470425 | 0.87 | TSHR (0.42) | TSHRTDP1ALDH1A1 | |
| SCHEMBL12262500 | 0.86 | TSHR (0.34) | TSHRTDP1MEN1LMNACYP3A4 | |
| SCHEMBL12544798 | 0.86 | TSHR (0.32) | TSHRALDH1A1 | |
| SCHEMBL12262427 | 0.86 | MAPT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051402-A1 | ALKYLATION OF PHENOLIC COMPOUNDS | THE UNIVERSITY OF SYDNEY (AU) | 2015-04-16 | — | — | WO | disclosed |