Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5130407 | 0.81 | ALDH1A1 (0.41) | ADORA2BALDH1A1LMNAHTTMAPT | |
| SCHEMBL5131623 | 0.78 | QPCT (0.44) | ADORA2BALDH1A1LMNAHTTRXFP1 | |
| SCHEMBL5132729 | 0.78 | ALDH1A1 (0.40) | ADORA2BALDH1A1LMNAHTTMAPT | |
| SCHEMBL5032099 | 0.77 | MAPT (0.47) | ADORA2BALDH1A1LMNAHTTMAPT | |
| SCHEMBL5033927 | 0.77 | ALDH1A1 (0.40) | ADORA2BALDH1A1LMNAHTTMAPT | |
| SCHEMBL13206028 | 0.76 | ALDH1A1 (0.37) | ADORA2BALDH1A1LMNAHTTMAPT | |
| SCHEMBL5035308 | 0.76 | MAPT (0.38) | ADORA2BALDH1A1LMNAHTTMAPT | |
| SCHEMBL14409871 | 0.75 | ALDH1A1 (0.41) | ADORA2BALDH1A1LMNAHTTMAPT | |
| SCHEMBL5133078 | 0.75 | ALDH1A1 (0.36) | ADORA2BALDH1A1LMNAHTTMAPT | |
| SCHEMBL5132704 | 0.75 | ALDH1A1 (0.43) | ADORA2BALDH1A1LMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3055313-B1 | CYCLIC THIENOURACIL CARBOXAMIDE AND ITS USE | Bayer Pharma AG (DE) | 2017-11-22 | — | — | EP | disclosed |
| EP-3055313-A1 | CYCLIC THIENOURACIL-CARBOXAMIDES AND USE THEREOF | Bayer Pharma Aktiengesellschaft (DE) | 2016-08-17 | — | — | EP | disclosed |
| WO-2015052065-A1 | CYCLIC THIENOURACIL-CARBOXAMIDES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2015-04-16 | — | — | WO | disclosed |