Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 3/20 | 0.63 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6743 | 0.81 | HTR7 (0.67) | HTR7CDK9DYRK1ADYRK2CHRNB2 | |
| SCHEMBL25028948 | 0.80 | HTR7 (0.65) | HTR7CDK9DYRK1ADYRK2CHRNB2 | |
| SCHEMBL7285 | 0.80 | HTR7 (0.65) | HTR7CDK9DYRK1ADYRK2CHRNB2 | |
| SCHEMBL12747708 | 0.80 | HTR7 (0.60) | HTR7CDK9DYRK1ADYRK2CHRNB2 | |
| SCHEMBL12747722 | 0.79 | HTR7 (0.58) | HTR7CDK9DYRK1ADYRK2CHRNB2 | |
| SCHEMBL23364685 | 0.79 | HTR7 (0.63) | HTR7CDK9DYRK1ADYRK2CHRNB2 | |
| SCHEMBL29932740 | 0.79 | HTR7 (0.63) | HTR7CDK9DYRK1ADYRK2CHRNB2 | |
| SCHEMBL1810138 | 0.78 | HTR7 (0.62) | HTR7CDK9DYRK1ADYRK2CHRNB2 | |
| SCHEMBL30438014 | 0.78 | HTR7 (0.62) | HTR7CDK9DYRK1ADYRK2CHRNB2 | |
| SCHEMBL18354457 | 0.78 | HTR7 (0.62) | HTR7CDK9DYRK1ADYRK2CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015052103-A1 | PESTICIDALLY ACTIVE N-IMINOPYRIDINIUM YLIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-16 | — | — | WO | disclosed |
| WO-2015052103-A1 | PESTICIDALLY ACTIVE N-IMINOPYRIDINIUM YLIDE COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-16 | — | — | WO | disclosed |