Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663634 | 0.72 | S1PR1 (0.35) | CYP11B1CYP11B2 | |
| SCHEMBL1661668 | 0.69 | S1PR1 (0.37) | CYP11B1CYP11B2 | |
| SCHEMBL1661180 | 0.68 | S1PR1 (0.38) | — | |
| SCHEMBL13614630 | 0.65 | CYP11B1 (0.41) | CYP11B1CYP11B2 | |
| SCHEMBL6882198 | 0.65 | CYP11B1 (0.41) | CYP11B1CYP11B2 | |
| SCHEMBL19824546 | 0.64 | CYP11B1 (0.43) | CYP11B1CYP11B2 | |
| SCHEMBL20310639 | 0.64 | CYP11B1 (0.43) | CYP11B1CYP11B2 | |
| SCHEMBL19261442 | 0.63 | CYP11B1 (0.42) | CYP11B1CYP11B2 | |
| SCHEMBL31224141 | 0.63 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL1662511 | 0.61 | APP (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2306994-A1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | Amgen, Inc (US) | 2011-04-13 | — | — | EP | disclosed |
| WO-2009154775-A1 | S1P1 RECEPTOR AGONISTS AND USE THEREOF | AMGEN INC. (US) | 2009-12-23 | — | — | WO | disclosed |