SCHEMBL13614630

SCHEMBL13614630

Fc1cc(C2OCCCO2)ccc1-c1cc(F)c(F)c(F)c1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 3/20 0.41
CYP11B2 P19099 3/20 0.41
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
PRKAB2 O43741 2/20 0.32
PRKAG1 P54619 2/20 0.32
PRKAA2 P54646 2/20 0.32
PRKAA1 Q13131 2/20 0.32
PRKAG3 Q9UGI9 2/20 0.32
PRKAG2 Q9UGJ0 2/20 0.32
PRKAB1 Q9Y478 2/20 0.32
PDE3B Q13370 1/20 0.32
PDE3A Q14432 1/20 0.32
CYP3A4 P08684 2/20 0.30
CYP2C9 P11712 1/20 0.30
APP P05067 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19261442 0.97 CYP11B1 (0.42) CYP11B1CYP11B2MEN1KMT2APRKAB2
SCHEMBL18487477 0.91 CYP11B1 (0.45) CYP11B1CYP11B2MEN1KMT2APRKAB2
SCHEMBL19824546 0.86 CYP11B1 (0.43) CYP11B1CYP11B2MEN1KMT2APRKAB2
SCHEMBL20310639 0.86 CYP11B1 (0.43) CYP11B1CYP11B2MEN1KMT2APRKAB2
SCHEMBL20209568 0.85 FFAR4 (0.33) CYP11B1CYP11B2
SCHEMBL17033199 0.84 CYP11B1 (0.33) CYP11B1CYP11B2
SCHEMBL19850827 0.82 CYP11B1 (0.47) CYP11B1CYP11B2MEN1KMT2APRKAB2
SCHEMBL18900926 0.82
SCHEMBL13433617 0.82 CYP11B1 (0.32) CYP11B1CYP11B2
SCHEMBL20083387 0.82 KDM1A (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3434750-B1 LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2020-11-18 EP disclosed
EP-3275972-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2019-06-19 EP disclosed
EP-3434750-A1 LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY ELEMENT JNC Corporation (JP) 2019-01-30 EP disclosed
EP-3088489-B1 LIQUID-CRYSTAL COMPOSITION AND LIQUID-CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2018-06-27 EP disclosed
EP-2933309-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2018-04-25 EP disclosed
EP-3006541-B1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY JNC CORP (JP) 2017-10-18 EP disclosed
EP-2116522-A1 PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CF<SB>2</SB>O BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY Chisso Corporation (JP) 2009-11-11 EP disclosed