Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PRKCG | P05129 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCH | P24723 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.36 |
| ▸ | TLR4 | O00206 | 1/20 | 0.34 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | NPY1R | P25929 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19479698 | 0.93 | MAPT (0.50) | MAPTSLC2A1PTGS1PTGS2PRKD3 | |
| SCHEMBL22750893 | 0.93 | MAPT (0.50) | MAPTSLC2A1PTGS1PTGS2PRKD3 | |
| SCHEMBL16638490 | 0.93 | MAPT (0.50) | MAPTSLC2A1PTGS1PTGS2PRKD3 | |
| SCHEMBL16149197 | 0.79 | MAPT (0.48) | MAPTSLC2A1PRKD3PRKCGPRKCB | |
| SCHEMBL17866090 | 0.78 | SLC2A1 (0.47) | MAPTSLC2A1PTGS1PTGS2PRKD3 | |
| SCHEMBL16148736 | 0.77 | MAPT (0.46) | MAPTSLC2A1PRKCATLR4LGALS8 | |
| SCHEMBL16148737 | 0.77 | MAPT (0.46) | MAPTSLC2A1PRKCATLR4LGALS8 | |
| SCHEMBL13561242 | 0.76 | SLC2A1 (0.51) | SLC2A1PTGS1PTGS2PRKD3PRKCG | |
| SCHEMBL10325671 | 0.76 | SLC2A1 (0.51) | SLC2A1PTGS1PTGS2PRKD3PRKCG | |
| SCHEMBL10325673 | 0.76 | SLC2A1 (0.51) | SLC2A1PTGS1PTGS2PRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9005578-B2 | Compounds and compositions for the detection and treatment of Alzheimer's disease and related disorders | FLUOROPHARMA, INC. (US) | 2015-04-14 | — | — | US | disclosed |