Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | PRKCG | P05129 | 1/20 | 0.37 |
| ▸ | PRKCB | P05771 | 1/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.37 |
| ▸ | PRKCH | P24723 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.37 |
| ▸ | TLR4 | O00206 | 1/20 | 0.35 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16638490 | 1.00 | MAPT (0.50) | MAPTSLC2A1PTGS1PTGS2PRKD3 | |
| SCHEMBL19479698 | 1.00 | MAPT (0.50) | MAPTSLC2A1PTGS1PTGS2PRKD3 | |
| SCHEMBL16638183 | 0.93 | MAPT (0.45) | MAPTSLC2A1PTGS1PTGS2PRKD3 | |
| SCHEMBL16149197 | 0.82 | MAPT (0.48) | MAPTSLC2A1PRKD3PRKCGPRKCB | |
| SCHEMBL17866090 | 0.81 | SLC2A1 (0.47) | MAPTSLC2A1PTGS1PTGS2PRKD3 | |
| SCHEMBL16148737 | 0.80 | MAPT (0.46) | MAPTSLC2A1PRKCATLR4LGALS8 | |
| SCHEMBL16148736 | 0.80 | MAPT (0.46) | MAPTSLC2A1PRKCATLR4LGALS8 | |
| SCHEMBL13561242 | 0.78 | SLC2A1 (0.51) | SLC2A1PTGS1PTGS2PRKD3PRKCG | |
| SCHEMBL10325673 | 0.78 | SLC2A1 (0.51) | SLC2A1PTGS1PTGS2PRKD3PRKCG | |
| SCHEMBL10325671 | 0.78 | SLC2A1 (0.51) | SLC2A1PTGS1PTGS2PRKD3PRKCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10857247-B2 | Compounds and compositions for the detection and treatment of Alzheimer's disease and related disorders | THE GENERAL HOSPITAL CORPORATION (US) | 2020-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10857247-B2 | Compounds and compositions for the detection and treatment of Alzheimer's disease and related disorders | APP, PSEN1, PSEN2 | MAPT 6/4885SLC2A1 367/4885PTGS1 2335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.