Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 5/20 | 0.47 |
| ▸ | HTR6 | P50406 | 5/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12480287 | 0.88 | HRH1 (0.57) | KMT2AMEN1KDM4EL3MBTL1MAPK1 | |
| SCHEMBL16638424 | 0.87 | KMT2A (0.62) | KMT2AMEN1LMNAKDM4EL3MBTL1 | |
| SCHEMBL12480779 | 0.85 | HRH1 (0.56) | KMT2AMEN1BCHEHRH1HTR6 | |
| SCHEMBL16638726 | 0.85 | SIRT2 (0.46) | KMT2AMEN1LMNAKDM4EL3MBTL1 | |
| SCHEMBL12480635 | 0.85 | HRH1 (0.67) | BCHEHRH1HTR6GRIN2DGRIN3B | |
| SCHEMBL17119768 | 0.83 | KMT2A (0.38) | KMT2AMEN1LMNAKDM4EL3MBTL1 | |
| SCHEMBL16638423 | 0.77 | KMT2A (0.58) | KMT2AMEN1LMNAKDM4EL3MBTL1 | |
| SCHEMBL13834008 | 0.77 | HRH1 (0.44) | KMT2AMEN1LMNAKDM4EL3MBTL1 | |
| SCHEMBL13293768 | 0.76 | HRH1 (0.58) | KMT2AMEN1KDM4EL3MBTL1MAPK1 | |
| SCHEMBL3236375 | 0.76 | HRH1 (0.58) | KMT2AMEN1LMNAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006263-B2 | Compounds and methods for treatment of hypertension | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-04-14 | — | — | US | disclosed |