Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 16/20 | 0.46 |
| ▸ | HRH1 | P35367 | 11/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 4/20 | 0.46 |
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | HTR7 | P34969 | 4/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16638454 | 0.88 | HTR6 (0.53) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL16638449 | 0.86 | HTR6 (0.54) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL12479317 | 0.85 | HTR6 (0.44) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL13834259 | 0.84 | HTR6 (0.56) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL12481033 | 0.84 | HTR6 (0.56) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL12480808 | 0.82 | HTR6 (0.56) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL12481037 | 0.81 | HTR6 (0.44) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL12480297 | 0.81 | HTR6 (0.46) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL12479660 | 0.81 | HTR6 (0.56) | HTR6HRH1ADRA2AHTR2AHTR2C | |
| SCHEMBL13221402 | 0.80 | HTR6 (0.58) | HTR6HRH1ADRA2AHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006263-B2 | Compounds and methods for treatment of hypertension | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-04-14 | — | — | US | disclosed |