Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.65 |
| ▸ | CASP2 | P42575 | 1/20 | 0.59 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.58 |
| ▸ | FAAH | O00519 | 3/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | ICMT | O60725 | 1/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | SELP | P16109 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12791952 | 1.00 | NAAA (0.65) | NAAACASP2DNM1FAAHCNR1 | |
| SCHEMBL12792130 | 1.00 | NAAA (0.65) | NAAACASP2DNM1FAAHCNR1 | |
| SCHEMBL12792143 | 1.00 | NAAA (0.65) | NAAACASP2DNM1FAAHCNR1 | |
| SCHEMBL889317 | 0.97 | NAAA (0.61) | NAAACASP2DNM1FAAHCNR1 | |
| SCHEMBL889316 | 0.97 | NAAA (0.61) | NAAACASP2DNM1FAAHCNR1 | |
| SCHEMBL889238 | 0.97 | NAAA (0.61) | NAAACASP2DNM1FAAHCNR1 | |
| SCHEMBL24412748 | 0.97 | NAAA (0.69) | NAAACASP2DNM1FAAHCNR1 | |
| SCHEMBL12792141 | 0.95 | NAAA (0.67) | NAAACASP2DNM1FAAHCNR1 | |
| SCHEMBL12791767 | 0.95 | NAAA (0.67) | NAAACASP2DNM1FAAHCNR1 | |
| SCHEMBL12791878 | 0.95 | NAAA (0.67) | NAAACASP2DNM1FAAHCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160009657-A1 | AMINE-CONTAINING LIPIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-14 | — | — | US | disclosed |
| US-9006487-B2 | Amine-containing lipids and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009657-A1 | AMINE-CONTAINING LIPIDS AND USES THEREOF | PHOSPHO1, CHMP4B, SGMS1 | NAAA 78/4885CASP2 3638/4885DNM1 946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.