Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PON1 | P27169 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16674128 | 0.92 | PON1 (0.46) | CYP19A1CYP11B1CYP11B2MAPTPON1 | |
| SCHEMBL12220255 | 0.87 | PON1 (0.43) | CYP19A1CYP11B1CYP11B2MAPTPON1 | |
| Iodide SCHEMBL2527838 | 0.85 | PON1 (0.42) | CYP19A1CYP11B1CYP11B2MAPTPON1 | |
| SCHEMBL12513967 | 0.84 | CYP11B1 (0.46) | CYP11B1CYP11B2MAPTPON1SMN1; SMN2 | |
| SCHEMBL667065 | 0.83 | PON1 (0.50) | CYP19A1CYP11B1CYP11B2MAPTTP53 | |
| Iodide SCHEMBL13735543 | 0.82 | PON1 (0.40) | CYP19A1MAPTPON1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL28638856 | 0.82 | PON1 (0.43) | CYP19A1CYP11B1CYP11B2MAPTPON1 | |
| Bromide SCHEMBL1179197 | 0.81 | PON1 (0.49) | CYP19A1CYP11B1CYP11B2MAPTTP53 | |
| SCHEMBL6890190 | 0.81 | PON1 (0.47) | CYP11B1CYP11B2MAPTPON1SMN1; SMN2 | |
| Water SCHEMBL31529728 | 0.81 | PON1 (0.49) | CYP19A1CYP11B1CYP11B2MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006303-B2 | Mesoporous polymer colloids | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-04-14 | — | — | US | disclosed |