Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PON1 | P27169 | 2/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18259778 | 0.96 | CYP11B1 (0.47) | PON1CYP11B1CYP11B2SMN1; SMN2MEN1 | |
| Water SCHEMBL18260008 | 0.95 | CYP11B1 (0.46) | PON1CYP11B1CYP11B2SMN1; SMN2MEN1 | |
| SCHEMBL20138573 | 0.83 | CYP11B1 (0.53) | PON1CYP11B1CYP11B2MEN1MAPT | |
| Hydrochloric Acid SCHEMBL2012582 | 0.82 | CYP11B1 (0.55) | PON1CYP11B1CYP11B2MEN1MAPT | |
| Water SCHEMBL18260003 | 0.82 | CYP11B1 (0.51) | PON1CYP11B1CYP11B2MEN1MAPT | |
| SCHEMBL16638701 | 0.81 | CYP19A1 (0.47) | PON1CYP11B1CYP11B2SMN1; SMN2MEN1 | |
| SCHEMBL16674128 | 0.80 | PON1 (0.46) | PON1CYP11B1CYP11B2SMN1; SMN2MEN1 | |
| SCHEMBL667065 | 0.76 | PON1 (0.50) | PON1CYP11B1CYP11B2SMN1; SMN2MEN1 | |
| SCHEMBL12220255 | 0.76 | PON1 (0.43) | PON1CYP11B1CYP11B2SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL383000 | 0.74 | PON1 (0.52) | PON1CYP11B1CYP11B2SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815562-B2 | REACTION OF NITROHALOGENS WITH ANILINES, A BASE AND A CATALYST, HYDROGENATION, | BAYER AKTIENGESELLSCHAFT (DE) | 2004-11-09 | — | — | US | disclosed |
| US-20040143138-A1 | Process for the preparation of nitrodiphenylamines | LANXESS DEUTSCHLAND GMBH (DE) | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040143138-A1 | Process for the preparation of nitrodiphenylamines | HNMT, PNMT, NNMT | PON1 3313/4885CYP11B1 146/4885CYP11B2 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.